CAS 59-46-1 Procaine China factory supply lower price high purity high quality 

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CAS 59-46-1 Procaine China factory supply lower price high purity high quality 

emily  
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Common Name    Procaine
CAS Number    59-46-1    Molecular Weight    236.310
Density    1.1±0.1 g/cm3    Boiling Point    373.6±22.0 °C at 760 mmHg
Molecular Formula    C13H20N2O2    Melting Point    61oC
 Density    1.1±0.1 g/cm3
Boiling Point    373.6±22.0 °C at 760 mmHg
Melting Point    61oC
Molecular Formula    C13H20N2O2
Molecular Weight    236.310
Flash Point    179.8±22.3 °C
Exact Mass    236.152481
PSA    55.56000
LogP    2.36
Vapour Pressure    0.0±0.8 mmHg at 25°C
Index of Refraction    1.543
Description    Procaine is a local anesthetic with a para-amino function. Sensitization mainly concerns medical, dental and veterinary professions.
Chemical Properties    The hydrochloride salt of 2-(diethylamino) ethyl p-aminobenzoate (C13H21ClN2O2 or N2C6H4COOCH2CH2NH(C2H5)2HCl) is generally referred to as procaine. Although the PABA ester is insoluble in water, the hydrochloride salt is very soluble in water.
Uses    Procaine (Novocain) is mainly used in dental or medical procedures requiring infiltration anesthesia, peripheral block, or spinal block.
Uses    Procaine is a sodium channel blocker and inhibitor of a variety of processes.
Definition    ChEBI:Procaine is a benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol. It has a role as a local anaesthetic, a central nervous system depressant, a peripheral nervous system drug and a drug allergen. It is a benzoate ester, a substituted aniline and a tertiary amino compound. It is functionally related to a 2-diethylaminoethanol and a 4-aminobenzoic acid. It is a conjugate base of a procaine(1+).
Procaine was synthesized in 1904 to address the chemical instabilityof cocaine and the local irritation it produced. The pKa of procaine is 8.9; it has low lipid solubility and the estergroup is unstable in basic solutions. Procaine is available inconcentrations ranging from 0.25% to 10% with pHs adjustedto 5.5 to 6.0 for chemical stability. Procaine is also includedin some formulations of penicillin G to decrease the pain ofintramuscular injection.
 

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