Neuropeptide Kisspeptin for sale with good quanity Activation of GnRH leads to release of FSH and LH

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Neuropeptide Kisspeptin

Cas:1848962-29-7

MF:C63H78N18O13 · xC2HF3O2

Purity:98% HPLC
Packing:2mg/vial and 5mg/vial;10vials/box
Min Order: 1box
Payment:Bitcoin,Moneygram and Wester Union
Lead time:24hours after received payment
Safe shipping to US and most of Europe country
Storage:Shading, confined preservation,2-8°C

What is Neuropeptide kisspeptin?
Neuropeptide Kisspeptin, also known as kiss1, was first identified in 1996 as a transfer suppressor in human cell lines.

The Kiss1 gene encodes a protein composed of 145 amino acids. In the human body, this protein is processed into a 54-amino acid peptide called kisspeptin, which, like several other neuropeptides, has a unique RF-amide motifs in its C-terminal region. It binds and activates the G-protein-coupled receptor GPR54, which stimulates hypothalamic neurons to release GnRH, leading to pituitary gonadotropin (LH and FSH) and sex hormone secretion.

Kisspeptin is a key regulator of the onset of puberty, regulation of sex hormone-mediated gonadotropin secretion, and fertility control. Inactivated or activated mutations in Kiss1 and GPR54 genes are associated with hypogonadotropin hypogonadism (IHH) and precocious puberty (CPP).

Neuropeptide kisspeptin has three main functions
Activation of GnRH neurons in the hypothalamus leads to GnRH release, which leads to the release of FSH and LH.
Inhibit the development of tumors.
Treat low libido.
How kisspeptin activates GnRH Neurons 
Bodybuilder is all too familiar with HPTA, the hypothalamic-pituitary-testicular axis whose positive and negative feedback controls the production and cessation of testosterone in men. HPGA is the hypothalamic-pituitary-gonadal axis. HPGA controls all stages of reproduction. The hypothalamus produces GnRH into the anterior pituitary and stimulates the secretion of LH and FSH. Slow GnRH pulsation is conducive to FSH secretion, while fast pulse frequency supports LH secretion.

What is the hypothalamic-Pituitary-gonadal axis (HPGA)? 
The positive and negative feedback of the hypothalamic-pituitary-gonadal axis (HPGA) controls the secretion and cessation of sex hormones in both men and women, and its normal work maintains the normal levels of sex hormones in both men and women, thus maintaining physiological functions. This is something that happens every day in the adult body, and HPGA plays an important role in adult men and women. However, HPGA is not form in adulthood; all its components are establish in the foetus, activate in the neonatal period, then become stationary in childhood and cannot reactivate until puberty.

 
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На Taki.Sale с октября 2023г.

Номер объявления 295071
Размещено: 14 мая 2024г.
Обновлено: 14 мая 2024г.
Актуально до: 14 мая 2025г.
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