The Neuro nootropic Peptide Semax for cerebral stroke Parkinson neurological defects

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Новий
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Доставка поштовими службами, Доставимо, Інше, Міжнародна доставка
https://www.astersteroids.com/the-neuronootropic-peptide-semax-benefits-dosage-and-use-in-bodybuilding/
Purity:98% HPLC
Packing:2mg/vial and 5mg/vial;10vials/box
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Storage:Shading, confined preservation,2-8°C

Nootropic Semax, while developed based on the corticotropin 4-10 fragment (ACTH4-10), is a powerful neuro nootropic peptide drug. It was approved by the Government of the Russian Federation in 2011 as part of the list of important and essential medicines in Russia, mainly for the treatment of central nervous system diseases (including stroke, transient ischemic attack, optic nerve disease, etc.), memory and cognitive impairments, and the strengthening of the immune system.

While Natural regulatory peptides are usually bioactive compounds produce by various cells. They provide connections between the major regulatory systems of the body, are direct regulatory substances or mediators of most physiological processes occurring in the body, and have a wide range of preventive and therapeutic effects. By modifying the natural regulatory peptide, it can have higher stability, so that it better apply in medical treatment. Nootropic Semax is a synthetic analogue of natural regulatory peptides.

What is ACTH?
Adrenocorticotropin (ACTH) and its fragments are one of the most active endogenous regulatory peptides. ACTH is a single chain polypeptide compose of 39 amino acids, which form in the anterior pituitary gland through the translation and processing of the precursor proteinogen melanocortin (POMC).

ACTH is one of the major regulatory components of the pituitary-hypothalamic axis and interacts with the regulatory system of the hypothalamus. It can enhance the synthesis and secretion of glucocorticoid.

In addition to its hormonal effects, ACTH also exhibits a wide range of extra-hormonal activities

Multiple studies have shown that ACTH and its fragments can affect the behavior of human and animals. ACTH accelerates the learning process of animals, and it may directly act on the central nervous system without relying on the activity of ACTH hormone.
A large number of studies have shown that the N-terminal region of ACTH is the main region responsible for the behavioral activity of hormones, while ACTH4-10 is the smallest fragment that retains the behavioral effect of ACTH molecule.
ACTH and its fragments show neuroprotective and neurotrophic effects in addition to the role of puzzle. Studies have shown that even small doses of ACTH can stimulate the growth of nerve fibers.
Peripheral nerve regeneration induced by ACTH and ACTH4-10 fragments was accompanied by significant enhancement of neuronal RNA and protein synthesis.
ACTH also enhanced RNA and protein synthesis and glucose utilization in the brains of older animals.
What is Nootropic Peptide Semax?
Product name:Semax    
Other name:Met-Glu-His-Phe-Pro-Gly-Pro
Cas:80714-61-0
MF:C 37 H 51 N 9 O 10 S
MW: 813.93
Purity :≥98%
The Origin of Nootropic Semax
The discovery of the remarkable intellectual, neuro protective, and neurotrophic effects of ACTH and its fragments makes this peptide one of the most promising candidates for the prevention and treatment of central nervous system diseases. However, these peptides are difficult to use in practice because of their extreme instability and short duration of action. The action time of ACTH4-10 is 30-60 min. After modification of different C-terminal, finding that the analogues carrying three C-terminal amino acids replace by Pro-Gly-Pro sequence show the longest activity. The peptide (h-met-glu-his-phi-pro-gly Pro-OH), is Semax, exhibits the intellectual-promoting effects of the natural prototype, while its action duration (Half-life) lasts 20-24 hours.
 
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