Pregabalin is a non-γ-aminobutyric acid (GABA) receptor agonist or antagonist. It is a novel calcium channel modulator that blocks voltage-dependent calcium channels and reduces neurotransmitter release. «Clinically, it is mainly used in neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, and as an adjuvant treatment for partial seizures in adults, generalized anxiety disorder, central neuralgia (including neuralgia associated with spinal cord injury, stroke, and multiple sclerosis), and fibromyalgia.»
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